Stems with sparse pubescence at nodes, usually fewer than 15 hairs per 0.1 sq. mm at most pubescent portion (excluding angle of petiole with stem). Leaf blades usually with fewer than 20 hairs per cm on length of midrib, fewer than 25 glands per 10 sq. mm between veins.

Roadsides, moist thickets, waste places, edges of woods; 0-2000 m; introduced; Man., N.B., N.S., Ont., P.E.I., Que.; Calif., Conn., Del., Ill., Ind., Maine, Md., Mass., Mich., Mo., N.H., N.J., N.Y., Ohio, Pa., R.I., Vt., Va., W.Va., Wis.

Humulus lupulus var. lupulus is indigenous to Europe. It has become established by introduction for ornament and for flavoring beer. Although not yet collected in all parts of the range, it should be expected, particularly as pistillate clones around abandoned homesteads. Humulus lupulus var. lupulus is reported from Oregon but no precise locality is known.